single-site analysis of nonlinear curve fitting Search Results


nanoanalyze data analysis software  (TA Instruments)
90
TA Instruments nanoanalyze data analysis software
Nanoanalyze Data Analysis Software, supplied by TA Instruments, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/single-site+analysis+of+nonlinear+curve+fitting/nanoanalyze+software/pmc05585709-488-13-11
Average 90 stars, based on 1 article reviews
nanoanalyze data analysis software - by Bioz Stars, 2026-08
90/100 stars
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itc llc data analysis program  (Malvern Panalytical)
99
Malvern Panalytical itc llc data analysis program
(A) Overview of the fragment-based development of CAM2602 to inhibit the Aurora A:TPX2 protein-protein interaction. The blue boxes highlight the key change(s) at each step. (B) Biophysical FP and <t>ITC</t> pK D values against Aurora A and Aurora B are shown for the compounds. (C) The X-ray crystal structure of fragment 3 bound to Aurora A is shown (red carbons; PDB: 8C1M) overlaid with the lead CAM2602 (purple carbons; PDB: 8C1K). (D) Complex of 3 (pink carbons; PDB: 8C15) with Aurora A with residues in the Tyr pocket highlighted. (E) Conservation of residues in the Tyr pocket between Aurora A and B with identical residues coloured in pale yellow and non-conserved residues coloured red, shown on Aurora A without a ligand (PDB: 1OL5) and on Aurora A in complex with 7 (PDB: 8C1G).. (F) Sequence alignment of human Aurora A and B with differences in residues indicated. Residues in red boxes are non-conserved.
Itc Llc Data Analysis Program, supplied by Malvern Panalytical, used in various techniques. Bioz Stars score: 99/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/single-site+analysis+of+nonlinear+curve+fitting/PEAQ-ITC/bio_rxiv__2023__03__22__533679-289-15-14
Average 99 stars, based on 1 article reviews
itc llc data analysis program - by Bioz Stars, 2026-08
99/100 stars
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itc data analysis software  (Malvern Panalytical)
86
Malvern Panalytical itc data analysis software
(A) Overview of the fragment-based development of CAM2602 to inhibit the Aurora A:TPX2 protein-protein interaction. The blue boxes highlight the key change(s) at each step. (B) Biophysical FP and <t>ITC</t> pK D values against Aurora A and Aurora B are shown for the compounds. (C) The X-ray crystal structure of fragment 3 bound to Aurora A is shown (red carbons; PDB: 8C1M) overlaid with the lead CAM2602 (purple carbons; PDB: 8C1K). (D) Complex of 3 (pink carbons; PDB: 8C15) with Aurora A with residues in the Tyr pocket highlighted. (E) Conservation of residues in the Tyr pocket between Aurora A and B with identical residues coloured in pale yellow and non-conserved residues coloured red, shown on Aurora A without a ligand (PDB: 1OL5) and on Aurora A in complex with 7 (PDB: 8C1G).. (F) Sequence alignment of human Aurora A and B with differences in residues indicated. Residues in red boxes are non-conserved.
Itc Data Analysis Software, supplied by Malvern Panalytical, used in various techniques. Bioz Stars score: 86/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/single-site+analysis+of+nonlinear+curve+fitting/10__1042_slash_bcj20220141-219-12-11
Average 86 stars, based on 1 article reviews
itc data analysis software - by Bioz Stars, 2026-08
86/100 stars
  Buy from Supplier

Image Search Results


(A) Overview of the fragment-based development of CAM2602 to inhibit the Aurora A:TPX2 protein-protein interaction. The blue boxes highlight the key change(s) at each step. (B) Biophysical FP and ITC pK D values against Aurora A and Aurora B are shown for the compounds. (C) The X-ray crystal structure of fragment 3 bound to Aurora A is shown (red carbons; PDB: 8C1M) overlaid with the lead CAM2602 (purple carbons; PDB: 8C1K). (D) Complex of 3 (pink carbons; PDB: 8C15) with Aurora A with residues in the Tyr pocket highlighted. (E) Conservation of residues in the Tyr pocket between Aurora A and B with identical residues coloured in pale yellow and non-conserved residues coloured red, shown on Aurora A without a ligand (PDB: 1OL5) and on Aurora A in complex with 7 (PDB: 8C1G).. (F) Sequence alignment of human Aurora A and B with differences in residues indicated. Residues in red boxes are non-conserved.

Journal: bioRxiv

Article Title: Selective inhibitors of the Aurora A-TPX2 protein-protein interaction exhibit in vivo efficacy as targeted anti-mitotic agents

doi: 10.1101/2023.03.22.533679

Figure Lengend Snippet: (A) Overview of the fragment-based development of CAM2602 to inhibit the Aurora A:TPX2 protein-protein interaction. The blue boxes highlight the key change(s) at each step. (B) Biophysical FP and ITC pK D values against Aurora A and Aurora B are shown for the compounds. (C) The X-ray crystal structure of fragment 3 bound to Aurora A is shown (red carbons; PDB: 8C1M) overlaid with the lead CAM2602 (purple carbons; PDB: 8C1K). (D) Complex of 3 (pink carbons; PDB: 8C15) with Aurora A with residues in the Tyr pocket highlighted. (E) Conservation of residues in the Tyr pocket between Aurora A and B with identical residues coloured in pale yellow and non-conserved residues coloured red, shown on Aurora A without a ligand (PDB: 1OL5) and on Aurora A in complex with 7 (PDB: 8C1G).. (F) Sequence alignment of human Aurora A and B with differences in residues indicated. Residues in red boxes are non-conserved.

Article Snippet: The raw ITC data were fitted using a single site binding model using the Microcal ITC LLC data analysis program in the Origin 7.0 package.

Techniques: Sequencing